An Ontology of Gene

نویسندگان

  • Hiroshi Masuya
  • Riichiro Mizoguchi
چکیده

The concept of a gene was established in the era of classical genetics and is now essential for life science for elucidating the molecular basis of the coding of genetic information necessary to realize the body of an organism and its biological functions. However, an ontology fully representing multiple aspects of a gene is still not available. In this study, we dissected the biological and ontological definitions of bearers of genetic information, including genes and alleles. Based on this analysis, we then proposed a basic way of modeling an ontology that represents the common definitions in classical and molecular genetics. This ontology is available at http://www.brc.riken.jp/lab/bpmp/ontology/ontology_gene.html.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Identification and prioritization genes related to Hypercholesterolemia QTLs using gene ontology and protein interaction networks

Gene identification represents the first step to a better understanding of the physiological role of the underlying protein and disease pathways, which in turn serves as a starting point for developing therapeutic interventions. Familial hypercholesterolemia is a hereditary metabolic disorder characterized by high low-density lipoprotein cholesterol levels. Hypercholesterolemia is a quantitativ...

متن کامل

An Executive Approach Based On the Production of Fuzzy Ontology Using the Semantic Web Rule Language Method (SWRL)

Today, the need to deal with ambiguous information in semantic web languages is increasing. Ontology is an important part of the W3C standards for the semantic web, used to define a conceptual standard vocabulary for the exchange of data between systems, the provision of reusable databases, and the facilitation of collaboration across multiple systems. However, classical ontology is not enough ...

متن کامل

Designing an Ontology for Knowledge Discovery in Iran’s Vaccine

Ontology is a requirement engineering product and the key to knowledge discovery. It includes the terminology to describe a set of facts, assumptions, and relations with which the detailed meanings of vocabularies among communities can be determined. This is a qualitative content analysis research. This study has made use of ontology for the first time to discover the knowledge of vaccine in Ir...

متن کامل

Query Architecture Expansion in Web Using Fuzzy Multi Domain Ontology

Due to the increasing web, there are many challenges to establish a general framework for data mining and retrieving structured data from the Web. Creating an ontology is a step towards solving this problem. The ontology raises the main entity and the concept of any data in data mining. In this paper, we tried to propose a method for applying the "meaning" of the search system, But the problem ...

متن کامل

How DoesStrawson Unify Epistemology, Ontology and Logic

Strawson’s conception of analysis as a ‘connective linguistic analysis’ makes it possible for him to achieve an indefinitely large range of ideas or concepts among them are certain numbers of fundamental, general and pervasive concepts or concept-types which not only are pre-theoretical or ahistorical, but also together constitute a structural framework only within whichlogic, ontology and epis...

متن کامل

Public Transport Ontology for Passenger Information Retrieval

Passenger information aims at improving the user-friendliness of public transport systems while influencing passenger route choices to satisfy transit user’s travel requirements. The integration of transit information from multiple agencies is a major challenge in implementation of multi-modal passenger information systems. The problem of information sharing is further compounded by the multi-l...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012